Barcode Verification – Minimizing potential dosing and dispensing errors starts with ensuring the accuracy of barcode artwork

BarProof - barcode verification

BarProof speeds barcode verification while ensuring accuracy   



Barcodes have changed very little over the last 60 years. Yet for pharmaceutical companies the barcode has taken on a vital role throughout the product’s lifecycle from initial packaging to patient distribution.


For pharmaceutical companies, a barcode helps to track and trace the origins of the drugs, which in turn helps in minimizing the chances of genuine drugs being considered spurious, sub-standard or counterfeit. Recognizing this fact, many nations are passing legislative initiatives to make it mandatory for pharmaceutical companies to imprint barcodes on primary level packaging.


During the packaging workflow, unlike text or artwork, the difference in a correct barcode versus a wrong barcode is often too subtle to be noticed by the human eye. However, a simple error in the barcode may cost the pharmaceutical company millions of dollars for a product recall and millions more in liability and loss of reputation if patient treatment is impacted. So proper barcode verification has become a virtual insurance policy ensuring you attain the highest level of accuracy of barcode in the manufacturer- pharmacy- patient continuum.


BarProof from Global Vision takes barcode verification quality control of barcodes to a whole new level of excellence. BarProof automatically locates all barcodes on a label or carton or press sheet and grades each according to CEN/ANSI/ISO standards and even verifies and decodes QR, linear, 1D and 2D barcodes.


To verify barcodes in the past, a manufacturer would inspect them one-by-one, with each barcode taking 20-to-30 seconds to inspect. For a press sheet that contains 60+ barcodes, it could easily take a manufacturer over 30 minutes to inspect just one sheet. This method is not efficient at all!


BarProof barcode verification tool has been developed to enable a manufacturer to inspect and evaluate an entire press sheet in one pass, taking only a minute or so to perform the inspection.


Global Vision’s BarProof Benefits

  • Verify an entire press sheet in one pass
  • Instantly locates and grades all barcodes on a press sheet
  • Simple to use
  • Color-coded reporting
  • Easily identifies pass / fail barcodes
  • ISO/ANSI/CEN compliant
  • 21CFR Part 11 compliant
  • No need for more hardware, use your existing Scan-TVS™ scanner


BarProof Grading Criteria

  • Decode – Checks if the scan line data can pass the reference code algorithm
  • Symbol Contrast – Checks the difference between the minimum and maximum reflectance of the scan line
  • Minimum Reflectance - Checks that the minimum reflectance is less than half of the maximum reflectance
  • Minimum Edge Contrast – Checks the smallest edge contrast found in the scan line
  • Modulation – Checks the ratio of the minimum edge contrast to the symbol contrast
  • Defects – Checks for reflectance non-uniformity along the scan line
  • Decodability – Checks the accuracy of the barcode printing and image in relation to the appropriate symbology reference decode algorithm


Moving forward, technology will make the barcode even more vital for the pharmaceutical industry. Healthcare providers are currently testing medication administration technologies (MATs) to ensure the patient’s safety, and liability for the organization. The MATs will rely upon barcodes to correctly identify the medication, dosage and will be linked to the patient’s electronic health record. These best practices are designed to improve patient safety by reducing the possibility of medication errors.

If this new technology is widely adopted, then pharmaceutical companies will most likely face stiffer penalties for not meeting barcode specifications.


Global Vision has been an innovator of barcode verification technologies for over two decades. They are the industry leaders in barcode verification solutions and their knowledge of pharmaceutical workflow processes has given them unique insight into the role of the simple barcode.


About Global Vision

Global Vision is the world leader in the design and delivery of Innovative Proofreading Technologies.

Our solutions are widely interoperable and have been integrated into the packaging workflows of leading consumer packaged goods companies, printing firms and over 72% of the major pharmaceutical industry worldwide.


Global Vision’s complete suite of advanced solutions featuring text-based, pixel-based, barcode and Braille inspection technologies are designed to eliminate printed artwork and copy related errors, providing end-to-end security at every stage of the packaging workflow. All our proofreading solutions meet FDA 21 CFR Part 11 / EMA Annex 11 requirements.


Headquartered in Montreal, Canada, Global Vision has worldwide representation. For more information or to request a WebEx demonstration of BarProof simply visit